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Sixty-four patients completed the study,32 in each group.Mean dose of BTA was 292 mouse units(first session)and 262 mouse units(second session).Mean dose of trihexyphenidyl was 16.25 mg.The changes on the Disability section of the Toronto Western Spasmodic Torticollis Rating Scale(TWSTRS- Disability)(primary outcome),Tsui Scale,and the General Health Perception Subscale were significantly in favor of BTA.More patients treated with BTA had an improvement of at least three points on the TWSTRS-Disability(14 versus 6)and on the Tsui Scale(23 versus 12).Adverse effects were significantly less frequent in the BTA group.BTA is significantly more effective in the treatment of ICD,with less adverse effects. |
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